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Pharmacological and Parenteral Therapies · Calculation · Take action

Dobutamine 250 mg in 250 mL D5W is prescribed at 5 mcg/kg/min for a client who weighs 80 kg. At what rate in mL/hr should the nurse set the pump?

mL/hr

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Answer: 24 mL/hr

Concentration: 250 mg ÷ 250 mL = 1 mg/mL = 1,000 mcg/mL. Dose: 5 × 80 = 400 mcg/min × 60 = 24,000 mcg/hr. Rate: 24,000 ÷ 1,000 = 24 mL/hr.

Source: Pickar. Dosage Calculations (weight-based titrations)

Keep practicing Pharmacological and Parenteral Therapies

This question is one of 182 Pharmacological and Parenteral Therapies items in NCLEXSim. On the NCLEX-RN, this category makes up 13–19% of the exam.

Study tip
  • Learn high-alert drugs by their hold parameters and antidotes: digoxin, warfarin (vitamin K), heparin (protamine), opioids (naloxone), insulin, potassium.
  • Do 10 dosage calculations a day: tablets, liquids, mL/hr, gtt/min, mg/kg, and units/hr. Convert units first, round last.

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