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Pharmacological and Parenteral Therapies · Calculation · Take action

A diltiazem infusion contains 125 mg in 125 mL. The prescribed dose is 10 mg/hr. At what rate should the nurse set the pump?

mL/hr

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Answer: 10 mL/hr

Concentration: 125 mg ÷ 125 mL = 1 mg/mL. Rate: 10 mg/hr ÷ 1 mg/mL = 10 mL/hr.

Source: Pickar. Dosage Calculations; FDA label: Diltiazem injection

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This question is one of 182 Pharmacological and Parenteral Therapies items in NCLEXSim. On the NCLEX-RN, this category makes up 13–19% of the exam.

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Study tip
  • Learn high-alert drugs by their hold parameters and antidotes: digoxin, warfarin (vitamin K), heparin (protamine), opioids (naloxone), insulin, potassium.
  • Do 10 dosage calculations a day: tablets, liquids, mL/hr, gtt/min, mg/kg, and units/hr. Convert units first, round last.

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